P21

Price range: S$349.00 through S$609.00

P21 (P021) is a CNTF-derived peptidomimetic investigated for neurogenesis and synaptic plasticity in rodent neurodegeneration models.

Formula
C27H42N6O8
MW
578.7
CAS
1246751-68-7

Ships in 1–2 business days · free shipping

Questions?

Purity is >99% (manufacturer's HPLC specification). Batch documentation is available on request — message @north_vial before you order.

For laboratory research use only. Not for human or animal consumption. Not approved by the HSA for therapeutic use.

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Description

P21, referenced in the scientific literature as P021, is a small peptidomimetic derived from an active region of ciliary neurotrophic factor (CNTF). An adamantylglycine residue was added to the C-terminus to increase lipophilicity and stability.

Preclinical work has investigated P021 for its effects on dentate gyrus neurogenesis and synaptic plasticity markers in rodents. Transgenic mouse models of Alzheimer’s-type pathology have been used to examine its influence on tau phosphorylation, cognitive performance and the leukaemia inhibitory factor (LIF) signalling pathway. It is used by researchers interested in small-molecule mimetics of neurotrophic factors. Comparisons with full-length CNTF help researchers distinguish the activity of the mimetic from that of the parent protein.

Keep lyophilised material sealed and cold.

Sold strictly as a research chemical for in-vitro and preclinical laboratory work. Not for human consumption or veterinary use.

Supplied as a 10-vial kit of lyophilised powder. Dispatched in 1–2 business days.

CAS number1246751-68-7
Molecular formulaC27H42N6O8
Molecular weight578.7 g/mol
Purity>99% (manufacturer's HPLC specification). Batch documentation on request.
FormLyophilised powder
Pack10 vials per kit
StorageStore at 2–8 °C, protected from direct sunlight and moisture. For long-term storage, −20 °C.
Intended useLaboratory research only. Not for human or animal consumption.

Product FAQ

What is P21?

P21 (P021) is a CNTF-derived peptidomimetic investigated for neurogenesis and synaptic plasticity in rodent neurodegeneration models.

What does a P21 kit contain and what does it cost?

P21 is sold as a kit of 10 vials of lyophilised (freeze-dried) powder, in 10 mg, 20 mg, 30 mg per vial. Prices run from S$349 to S$609 per 10-vial kit, with free shipping.

What are the CAS number and molecular formula of P21?

P21 has CAS number 1246751-68-7, molecular formula C27H42N6O8, molecular weight 578.7 g/mol.

How should P21 be stored?

Store the sealed vials at 2–8 °C, protected from direct sunlight and moisture; for long-term storage, −20 °C is standard practice. Once reconstituted, keep refrigerated and use within the period appropriate to the compound.

What purity is P21?

Purity is >99% (manufacturer's HPLC specification). Batch documentation is available on request — message @north_vial before you order.

Is P21 for human or animal use?

No. P21 is supplied strictly as a laboratory reference material for in-vitro research use only — not for human or animal consumption, and not approved for therapeutic use.

How fast does P21 ship and how do I pay?

Shipping is free. Orders are dispatched in 1–2 business days and usually delivered in 6–9 business days. Payment is by cryptocurrency: Bitcoin (BTC), or USDT/USDC/ETH on the Ethereum (ERC-20) network.