ACE-031

S$1,179.00

ACE-031 is a soluble activin receptor type IIB–Fc fusion protein that binds TGF-β superfamily ligands, used in preclinical SMAD2/3 signalling research.

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Purity is >99% (manufacturer's HPLC specification). Batch documentation is available on request — message @north_vial before you order.

For laboratory research use only. Not for human or animal consumption. Not approved by the HSA for therapeutic use.

SKU: N/A Category: Growth Hormone Axis

Description
Specifications

Description

ACE-031 (ramatercept) is a fusion protein that joins the extracellular ligand-binding domain of activin receptor type IIB (ActRIIB) to the Fc region of human immunoglobulin G1. It acts as a soluble decoy receptor, or ligand trap, for several members of the TGF-β superfamily.

Ligands captured by ActRIIB include activin A and activin B, growth differentiation factors GDF-8 and GDF-11, and certain bone morphogenetic proteins. By sequestering them before they reach cell-surface receptors, ACE-031 reduces activation of the ALK4 and ALK5 type I receptor kinases and the phosphorylation of SMAD2 and SMAD3. Preclinical research uses it to dissect ligand-specific signalling, receptor–ligand binding and SMAD-dependent transcription in cell and rodent models.

Keep the lyophilised protein sealed and frozen.

For use by qualified researchers in a laboratory setting only. Not intended for human or veterinary use of any kind.

Supplied as a 10-vial kit of lyophilised powder. Dispatched in 1–2 business days.

Purity	>99% (manufacturer's HPLC specification). Batch documentation on request.
Form	Lyophilised powder
Pack	10 vials per kit
Storage	Store at 2–8 °C, protected from direct sunlight and moisture. For long-term storage, −20 °C.
Intended use	Laboratory research only. Not for human or animal consumption.

Product FAQ

What is ACE-031?

ACE-031 is a soluble activin receptor type IIB–Fc fusion protein that binds TGF-β superfamily ligands, used in preclinical SMAD2/3 signalling research.

What does a ACE-031 kit contain and what does it cost?

ACE-031 is sold as a kit of 10 vials of lyophilised (freeze-dried) powder, in 1 mg per vial. The price is S$1,179 per 10-vial kit, with free shipping.

How should ACE-031 be stored?

Store the sealed vials at 2–8 °C, protected from direct sunlight and moisture; for long-term storage, −20 °C is standard practice. Once reconstituted, keep refrigerated and use within the period appropriate to the compound.

What purity is ACE-031?

Purity is >99% (manufacturer's HPLC specification). Batch documentation is available on request — message @north_vial before you order.

Is ACE-031 for human or animal use?

No. ACE-031 is supplied strictly as a laboratory reference material for in-vitro research use only — not for human or animal consumption, and not approved for therapeutic use.

How fast does ACE-031 ship and how do I pay?

Shipping is free. Orders are dispatched in 1–2 business days and usually delivered in 6–9 business days. Payment is by cryptocurrency: Bitcoin (BTC), or USDT/USDC/ETH on the Ethereum (ERC-20) network.