Description
Thymosin alpha-1, also known by its non-proprietary name thymalfasin, is a 28-amino-acid peptide with an acetylated N-terminus. It was first isolated from thymosin fraction 5, a calf thymus extract, and corresponds to the N-terminal region of the larger precursor protein prothymosin alpha.
Preclinical research has investigated thymosin alpha-1 as a modulator of immune signalling. In-vitro studies have examined its interaction with Toll-like receptor pathways in dendritic cells and macrophages, its influence on T-cell maturation markers and its effects on cytokine production, while rodent infection models have been used to study immune parameters in vivo. Comparisons with prothymosin alpha and with shorter synthetic fragments help researchers locate the active region of the sequence.
Keep vials sealed and refrigerated or frozen, away from light.
Research chemical only. The summary above reflects published preclinical literature and is not a statement of suitability for any human or veterinary use.
Supplied as a 10-vial kit of lyophilised powder. Dispatched in 1–2 business days.
